This webinar will explore familial patterns of pancreatic cancer, hereditary risk and precursors for pancreatic cancer. This webinar was recorded on March 11, 2015. The presenter is Teresa A. Brentnall, MD – University of Washington

We were fortunate to have Tanya Dwarte, Clinical Research Coordinator from the Garvan Institute of Medical Research, present on the Pancreatic Cancer Familial Screening Program for high-risk individuals, at our recent online Patient Support Group.

A highly informative session, Tanya provided an overview of the program, along with insight into eligibility for recruitment, process and tests involved and benefits gained from inclusion in the trial.

This video is a recording of the presentation made by Tanya Dwarte at our recent online Patient Support Group - Thursday 20th August, 2020

1. BRCA Mutations:
BRCA Gene Mutations. Sometimes, changes or “mutations” occur that prevent genes from doing their job properly. Certain mutations in the BRCA genes make cells more likely to divide and change rapidly, which can lead to cancer.

2. FAMMM Syndrome:
Familial Atypical Multiple Mole Melanoma syndrome (FAMMM syndrome) is an autosomal dominant disorder characterized by the presence of multiple large moles of variable size and color with pigmentary leakage, associated with an increased incidence of malignant melanoma, pancreatic carcinoma

3. Peutz-jeghers syndrome:
Peutz-Jeghers syndrome (PJS) is characterized by the association of gastrointestinal (GI) polyposis and mucocutaneous pigmentation.

4. Lynch syndrome:
Peutz-Jeghers syndrome (PJS) is characterized by the association of gastrointestinal (GI) polyposis and mucocutaneous pigmentation.

5. Familial pancreatitis
Hereditary pancreatitis is a genetic condition characterized by recurrent episodes of inflammation of the pancreas.

Genetic testing is used by doctors to identify them.

#cancer #pancreaticcancer #pancreas #cancersurgeon #pancreatic #cancertreatment #cancercauses #drpraveenkammar

Dr. Steven Hochwald presents on hereditary syndromes and pre-malignant states of pancreatic cancer.

Genetics experts at The James are collaborating with pancreatic cancer specialists and their patients to study certain genetic mutations that, when identified, may help the families of pancreatic cancer patients.

Familial/Hereditary Pancreatic Cancer Surveillance Programs: An Overview
Presented by Carrie Mansfield, MBA, Clinical Marketing Program Manager

0:00 Introduction
0:14 Statistics for pancreatic cancer
1:00 Surveillance programs are effective at detecting PDAC earlier
2:04 Definition: Familial and Hereditary Pancreatic Cancer
2:43 Definition: Screening vs Surveillance
3:38 Familial and Hereditary relative risk for Pancreatic cancer
4:27 Surveillance guidelines for those at high risk for pancreatic cancer
5:39 Guidelines for conducting pancreatic cancer surveillance
6:23 Analysis of the efficiency of imaging during surveillance (publications)
7:23 The role(s) that IMMray® PanCan-d could play
8:22 Surveillance programs in North America
8:34 The PanFAM study
8:55 Summary