What do we know about acute lymphoblastic leukemia (ALL) development and treatment?

Know ALL was pleased to speak to Charles Mulligan, St Jude Children's Research Hospital, Memphis, US. We asked, What do we know about acute lymphoblastic leukemia (ALL) development and treatment?

Mulligan explains what ALL is and how the affected cells change and lead to symptoms. He describes how treatments are administered to patients and why. Mulligan outlines groups of patients that are at risk of ALL development and the impact age has on this. Finally, he discusses how the treatment of ALL has changed over the years and highlights the success of chimeric antigen receptor (CAR) T-cell therapy.