Localized amyloidosis: symptoms and site of disease

Localized amyloidosis is typically immunoglobulin light chain ****ociated (AL), although serum amyloid A protein and transthyretin have also been reported as causing localized disease. Localized amyloidosis often involves the laryngo-tracheobronchial tree, urogenital tract, and skin. Eli Muchtar, MD, Mayo Clinic, Rochester, MN, discusses localized amyloidosis compared to systemic amyloidosis, with localized amyloidosis diagnosis based on symptoms and site of localized disease. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).