I am Passent a CTCL fighter. The video highlights the process of CTCL diagnosis.

Maintenance therapy options for cutaneous T-cell lymphomas could be improved. Here, Rudolf Stadler, MD, PhD, of the University Medical Center Minden, Minden, Germany, discusses the RESMAIN study (NCT02953301), investigating resminostat as a maintenance therapy for advanced mycosis fungoides or Sézary syndrome. This video was recorded at the European Organisation for the Research and Treatment of Cancer (EORTC) Cutaneous Lymphoma Task Force (CLTF) 2018 Congress, held in St. Gallen, Switzerland.

Pushkal Garg, MD, Chief Medical Officer at Alnylam discusses hereditary ATTR (hATTR) amyloidosis, a rare condition that affects an estimated 50,000 people worldwide. Symptoms can affect multiple parts of the body, including the nervous (nerve), cardiac (heart), and gastrointestinal (digestive) systems.

Amyloidosis refers to a group of conditions caused by the build-up of amyloid fibrils in the body. Each type is caused by a different misfolded protein. There are multiple types of amyloidosis, including amyloid A (AA) amyloidosis and amyloid light chain (AL) amyloidosis, which are the most common.

hATTR amyloidosis is caused by a gene change (mutation) that affects the function of a protein in the blood called transthyretin (TTR). This protein is made primarily in the liver. The symptoms of hATTR amyloidosis can vary widely among people with the same mutation and even within families, though some do see a pattern of symptoms develop. Different symptoms may appear at different times for each individual. The age that initial symptoms appear may vary, ranging from the mid-20s to the mid-60s.

hATTR amyloidosis affects several parts of the body, including:
- The peripheral nervous system, which is made up of nerves that branch out from the brain and spinal cord and communicate with the rest of the body including your arms and legs
- The cardiac system, which includes the heart and blood vessels, transports blood through veins and delivers oxygen to cells in the body
- The autonomic nervous system, which is made up of nerves that connect the brain and spinal cord to organs such as the heart, stomach, and intestines, and helps to control bodily functions such as breathing, digestion, and heart rate

There are therapies available that address the underlying cause of hATTR amyloidosis. These treatments can help by decreasing the amount of TTR protein that’s made in the body. Liver transplant is also an option for some patients who meet certain eligibility criteria. Due to the progressive nature of hereditary ATTR (hATTR) amyloidosis, managing symptoms is an ongoing process. Physicians may prescribe medications to treat some of these symptoms and reduce the daily impact they may have.

Onpattro (patisiran) treats the polyneuropathy caused by an illness called hereditary transthyretin-mediated amyloidosis and is indicated for adults only.

The Global Kaposi Sarcoma Market is expected to grow at a CAGR during the forecasting period (2020-2027).

Kaposi sarcoma refers to a type of cancer that develops from the cells lining blood vessels or lymph nodes. The cancer usually appears as tumors on mucosal surfaces or on the skin, but can also develop in body parts such as the digestive tract, or the lungs. The abnormal Kaposi sarcoma cells cause brown, purple, or red blotches on the skin, called lesions. The growing prevalence of the Kaposi Sarcoma and the rising number of patients undergoing organ transplantation procedures as patients undergoing organ transplantations are more susceptible for Kaposi sarcoma, are the major factor attributing the growth of the Kaposi sarcoma market.


#KaposiSarcomaMarketSize #KaposiSarcomaMarketShare

Pierluigi Porcu, MD, Jefferson Health, Sidney Kimmel Cancer Center, Philadelphia, PA, discusses ongoing research in the field of cutaneous T-cell lymphoma (CTCL). Dr Porcu highlights several interesting areas being explored, including genomic research using single-cell analysis, the tumor microenvironment, and studies exploring the potential role of MRD as a strategy to redefine disease stage. This interview took place at the 17th International Conference on Malignant Lymphoma (ICML), held in Lugano, Switzerland.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

Desmoid Tumor Awareness video

Like countless others, Michael Reddy turned to the Kushi Institute after receiving devastating news. In July of 2014, Michael Reddy, a happily married father of two, went to the doctor for a routine check-up. Much to his surprise, Michael learned that he had Stage 4 Appendix Cancer. The doctors informed Michael that he had a 50/50 chance of survival because the cancer was spreading. Michael's mother immediately advised him to see a Macrobiotic Counselor in Los Angeles. After implementing a healing diet and lifestyle changes, Michael and his family began to see and feel a huge difference. The effects were so profound that both he and his mother were inspired to attend courses at the Kushi Institute. Michael joined us for two of our flagship programs, Way to Health and Macrobiotic Leadership, while his mother attended Way to Health and is returning in the spring to continue her education. Meanwhile, back in Los Angeles, Michael's wife started a Macrobiotic Group and has organized events with Jessica Porter, author of The Hip Chick's Guide to Macrobiotics, among others. We are pleased to announce that Mike's cancer has shrunk and he is on his way to recovery. Get inspired, watch the video!!

February 1st 2007 our lives were changed forever. Our 15 year old daughter Nicolette (Nikki) was diagnosed with ewings sarcoma. For about 6 months Nikki was complaining of lower back pain off and on. The pain would go away with Motrin and sometimes be gone for a few weeks at a time so the doctor said to stop doing sit ups (she did 100 a day) and not to run on the treadmill and see what happens. Then on Feb.1st she said the pain was so bad she can't sit in the chairs at school. That morning I took her back to the doctor and she sent us for a MRI that day. A few hours later the phone rang with the doctor telling us to pack a bag and get to Children's Memorial Hospital that something was seen on the MRI. Since that day she has had several procedures, scans, MRI, and biopsy. Due to the location in her spine it is inoperable. She has completed 9 rounds of chemotherapy out of 14 all inpatient and she has just finished 31 radiation treatments. She loves shopping, listen to Bob Dylan, and horseback riding. Her older sister is her best friend and as she says her 2 younger sisters are annoying. Nikki is an inspiration to all of us with her strength and her constant negotiations with the doctor to move chemo for a week or two due to what she calls more important things. They gave in this time so she could start her Junior year but it's going to be the last time. As with all these amazing kids life has been a roller coaster this past year in and out of the hospital, low counts, fevers,complications from radiation and the list goes on and so do we! Our kids give us the strength to get out of bed everyday. They have every reason in the world to complain and stay in bed but all they care about is getting to the mall or going to school that's the last thing they want to do is lay around another day. God has given us our special ANGELS to teach us all a lesson. Live everyday to it's fullest and never give in because they sure as heck aren't going to :-)

Stanford's team of neurosurgeons talk about their work with patients and the care they provide at Stanford's Brain Tumor Center.

Early this summer television anchor Robin Roberts made a tearful announcement.

"As many of you know, five years ago I beat breast cancer. Now sometimes treatment for cancer can lead to other serious medical issues and that's what I'm facing right now. It is something called MDS- Myelodysplastic Syndrome," says Robin Roberts.
That's when she put a face to myelodysplastic syndrome. MDS is a collection of blood disorders most people have never heard of.

"Myelodysplastic Syndrome is kind of under the radar because in some ways it's a malignancy but it's really a disorder of the bone marrow that causes a failure to produce the normal cells in the bone marrow. The older term is pre-leukemia because some, but not all, patients over time will evolve into an acute leukemia," says Dr. William Harwin, oncologist on Lee Memorial Health System's medical staff.

Not quite a cancer itself, it has shares many characteristics.

"An uncontrolled proliferation, which cells don't have the normal stops and normal controls and it's also at the same time a capacity to spread to the parts of the body where they normally don't belong," says Dr. Harwin.

Question is, what causes the breakdown of blood production. Scientists determined the disease can stem from previous cancer treatment. That's what Roberts believes happened to her.

"Most of the time we really don't know why. There's some situations where this can actually be a consequence or a late manifestation in someone who had chemotherapy several years before. It can be related to radiation in rare situations," says Dr. Harwin.

The only cure for MDS is a bone marrow transplant; the route Roberts took. Far more people will manage it as a chronic condition. Despite it's reputation as pre-leukemia, only 30% of cases will make that evolution.

View More Health Matters video segments at leememorial.org/healthmatters/

Lee Memorial Health System in Fort Myers, FL is the largest network of medical care facilities in Southwest Florida and is highly respected for its expertise, innovation and quality of care. For nearly a century, we've been providing our community with everything from primary care treatment to highly specialized care services and robotic assisted surgeries.

Visit leememorial.org