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Esophageal cancer staging
Esophageal cancer staging administrator 2 Views • 2 years ago

Today, CancerBro will explain esophageal or esophagus cancer staging. <br /><br />Video Transcript:<br /><br />The staging system used for esophageal cancer is known as TNM staging system. <br /><br />This diagram is a magnified image of cross-sectiob of wall of esophagusm. Imagine the upper part is the inner side and lower part is outer side. <br /><br />The innermost layer is called as epithelium, followed by this layer, called as lamina propria.<br /><br />Outer to the lamina propria, is this layer called as muscularis mucosa. <br /><br />Outer to which, lies this layer which is called as submucosa. Then lies muscularis propria. <br /><br />And on the outermost aspect, lies this layer which is called as serosa or adven****ia. <br /><br />Now, let&#039;s discuss the T-staging for esophageal cancer. <br /><br />First is Tis, or carcinoma in situ. This is not considered malignant, and is localised to epithelium.<br /><br />Infiltration of lamina propria or muscularis mucosa is called as T1a disease. <br /><br />Infiltration into submucosa is called as T1b. Muscularis propria infiltration is called as T2. And infiltration of serosa or adven****ia is called as T3. <br /><br />Till T3 disease, the cancer is limited to the wall of esophagus, and does not extend outside to involve adjacent structures. <br /><br />Whereas in T4 disease, the cancer infiltrates through the wall of esophagus and involves adjacent structures, like in this figure, the cancer has infiltrated into the heart or pericardium.<br /><br />And here, it has infiltrated into the lungs or pleora. And here it infiltrates the diaphragm. It may also infiltrate anteriorly, into the trachea. Or into the great vessels of heart. <br /><br />So this finishes the T-stage, now let&#039;s come to the N-stage. <br /><br />N staging maybe N1, N2 or N3, depending upon the number of lymph nodes involved. <br /><br />Last comes the M or the metastatic staging, which determines the spread of cancer to distance sites. Like in this figure, the cancer has spread to involve both the lungs. And here it has spread to the liver in form of multiple nodular deposits. <br /><br />Rarely, the cancer may spread to bones.<br /><br />So this completes the TNM staging for esophageal cancer. <br /><br />CancerBro is also active on most social media channels. Follow him to get rich and authoritative content related to cancer awareness, risk factors, symptoms, diagnosis, treatment, etc. <br /><br />Facebook - https://www.facebook.com/officialcancerbro<br />Instagram - https://www.instagram.com/official_cancerbro<br />Twitter - https://twitter.com/cancer_bro/<br />Website - http://www.cancerbro.com/

Stomach cancer staging
Stomach cancer staging administrator 4 Views • 2 years ago

Watch this video to know what are the various stages of stomach cancer. <br /><br />Video Transcript:<br /><br />Now, after discussing the different layers of stomach wall, let&#039;s discuss the T-staging of the stomach cancer.<br /><br />First is the Tis ot carcinoma in situ. This is not considered as malignant, and is localised to epithelium. <br /><br />Infiltration of lamina propria or muscularis mucosa is called as T1a disease. <br /><br />Infiltration into the submucosa is called as T1b. Muscularis propria infiltration is called as T2. <br /><br />Infiltration of subserosa is called as T3. And infiltration of the tumor into the serosa is called as T4a disease. <br /><br />When the tumor extends through the stomach walls to involve the adjacent structures it is called as T4b. <br /><br />In this figure the tumor extends to involve the colon. And here it infiltrates the pancreas. And here the tumor infiltrates into the spleen. And here it invades the kidney. It may also infiltrate into the liver or the diaphragm.<br /><br />This finishes the T staging of the stomach cancer, now next comes the N staging or the nodal staging. <br /><br />The regional nodes which drain the stomach are different in different part of stomach. <br /><br />These nodes drain the lesser curvature of the stomach. And these drain the upper part of the greater curvature of the stomach. And these the lower part. <br /><br />These nodes drain the pyloric antrum. All the nodes draining the different part of the stomach, ultimately drain into these nodes which is called as the coeliac nodes. <br /><br />M staging refers to the distance spread of the tumor to different parts of the body.<br /><br />DistanT metastasis maybe seen to the liver. The peritoneum in form of multiple peritoneal deposits. <br /><br />To the lungs in form of multiple nodular deposits. Rarely, it may spread to the left supraclavicular lymph node which presents as nodular deposits in the left side of the neck.<br /><br />Or a nodular deposit in the periumbilical region, called as sister Mary Joseph nodule. <br /><br />It may also present as pelvic deposits in the rectovesical pouch or pouch of douglas. <br /><br />Or as nodular deposits in one or both the ovaries, called as Krukenberg&#039;s tumor. Very rarely, it may also spread to brain or bones. <br /><br />This finishes the TNM staging for stomach cancer. <br /><br />CancerBro is also active on social media channels. Follow him to get rich and authoritative content related to cancer awareness, risk factors, symptoms, diagnosis, treatment, etc. <br /><br />Facebook - https://www.facebook.com/officialcancerbro<br />Instagram - https://www.instagram.com/official_cancerbro<br />Twitter - https://twitter.com/cancer_bro/<br />Website - http://www.cancerbro.com/

Treatment of Bladder Cancer by Stage
Treatment of Bladder Cancer by Stage administrator 4 Views • 2 years ago

Most of the time, treatment of bladder cancer is based on the tumor’s clinical stage when it&#039;s first diagnosed. This includes how deep it&#039;s thought to have grown into the bladder wall and whether it has spread beyond the bladder. Other factors, such as the size of the tumor, how fast the cancer cells are growing (grade), and a person’s overall health and preferences, also affect treatment options.<br /><br />Treating stage 0 bladder cancer<br />Stage 0 bladder cancer includes non-invasive papillary carcinoma (Ta) and flat non-invasive carcinoma (Tis or carcinoma in situ). In either case, the cancer is only in the inner lining layer of the bladder. It has not invaded (spread deeper into) the bladder wall.<br /><br />This early stage of bladder cancer is most often treated with transurethral resection (TURBT) with fulguration followed by intravesical therapy within 24 hours.<br /><br />Stage 0a<br />Sometimes no further treatment is needed. Cystoscopy is then done every 3 to 6 months to watch for signs that the cancer has come back.<br /><br />For low-grade (slow-growing) non-invasive papillary (Ta) tumors, weekly intravesical chemotherapy may be started a few weeks after surgery. If the cancer comes back, the treatments can be repeated. Sometimes intravesical chemo is repeated over the next year to try to keep the cancer from coming back.<br /><br />High-grade (fast-growing) non-invasive papillary (Ta) tumors are more likely to come back after treatment, so intravesical BCG is often used after surgery. Before it&#039;s given, TURBT is commonly repeated to be sure the cancer has not affected the muscle layer. BCG is usually started a few weeks after surgery and is given every week for several weeks. Intravesical BCG seems to be better than intravesical chemotherapy for high-grade cancers. It can help both keep these cancers from coming back and keep them from getting worse. But it also tends to have more side effects. It, too, may be done for the next year or so.<br /><br />Stage 0 bladder cancers rarely need to be treated with more extensive surgery. Partial or complete cystectomy (removal of the bladder) is considered only when there are many superficial cancers or when cancer continues to grow (or seems to be spreading) despite treatment.<br /><br />Stage 0is<br />For flat non-invasive (Tis) tumors, intravesical BCG is the treatment of choice after TURBT. Patients with these tumors often get 6 weekly treatments of BCG, starting a few weeks after TURBT. Some doctors recommend repeating BCG treatment every 3 to 6 months.<br /><br />Follow-up and outlook after treatment<br />After treatment for any stage 0 cancer, close follow-up is needed, with cystoscopy about every 3 months for a least a couple of years to look for signs of the cancer coming back or new bladder tumors.<br /><br />The outlook for people with stage 0a (non-invasive papillary) bladder cancer is very good. These cancers can be cured with treatment. During long-term follow-up care, more superficial cancers are often found in the bladder or in other parts of t

Treatment Options for Oral Cavity and Oropharyngeal Cancer by Stage
Treatment Options for Oral Cavity and Oropharyngeal Cancer by Stage administrator 4 Views • 2 years ago

Treatment Options for Oral Cavity and Oropharyngeal Cancer by Stage<br />This information is based on AJCC Staging systems prior to 2018 which were primarily based on tumor size and lymph node status. Since the updated staging system for oropharyngeal cancer now also includes the p16 status of the tumor, the stages may be higher or lower than previous staging systems. Whether or not treatment strategies will change with this new staging system are yet to be determined. You should discuss your stage and treatment options with your physician. <br /><br />The type of treatment your doctor will recommend depends on where the tumor is and how far the cancer has spread. Here are common ways to treat different stages of oral cavity and oropharyngeal cancer. But each situation is different. Your doctor may have reasons for suggesting a treatment option not mentioned here.<br /><br />Most experts agree that treatment in a clinical trial should be considered for any type or stage of cancer in the head and neck areas. This way people can get the best treatment available now and may also get the new treatments that are thought to be even better.<br /><br />Stage 0 (carcinoma in situ)<br />Although cancer in this stage is on the surface layer and has not started to grow into deeper layers of tissue, it can do so if not treated. The usual treatment is surgery (usually Mohs surgery, surgical stripping, or thin resection) to remove the top layers of tissue along with a small margin (edge) of normal tissue. Close follow-up is important to watch for signs that the cancer has come back. Carcinoma in situ that keeps coming back after surgery may need to be treated with radiation therapy.<br /><br />Nearly all people with this stage survive a long time without the need for more intense treatment. Still, it&#039;s important to note that continuing to smoke increases the risk that a new cancer will develop.<br /><br />Stages I and II<br />Most patients with stage I or II oral cavity and oropharyngeal cancer do well when treated with surgery and/or radiation therapy. Chemotherapy (chemo) given along with radiation (called chemoradiation) is another option. It can be used alone, but it&#039;s most often used after surgery to treat any cancer cells that may be left behind. Both surgery and radiation work well in treating these cancers. The choice depends on your preferences and the expected side effects, including how the treatment might affect how you look and how you swallow and speak.<br /><br />Lip<br />Surgery is preferred for small cancers that can be removed. Radiation alone may also be used as the first treatment. In this case, surgery might be needed later if radiation doesn’t completely get rid of the tumor.<br /><br />Large or deep cancers often require surgery. If needed, reconstructive surgery can help correct the defect in the lip.<br /><br />If the tumor is thick, it increases the risk that the cancer might have spread to lymph nodes in the neck, so the surgeon may remove them (called lymph node dissection) so they can be checked for cancer spread.<br />

Oculoplastic Surgery | Best Oculoplastic Surgeon | Eyelid Surgery| Blepharoplasty - Dr. Debraj Shome
Oculoplastic Surgery | Best Oculoplastic Surgeon | Eyelid Surgery| Blepharoplasty - Dr. Debraj Shome administrator 0 Views • 2 years ago

Oculoplastic Surgery or Eye Plastic Surgery is a super-specialty of ophthalmology & plastic surgery, which focuses on plastic surgery of the eyes, eyelid, orbit (bony socket surrounding eyes), lacrimal area & the mid-face. Oculoplastic surgeons train in both eye surgery & plastic & cosmetic surgery and hence they are the best at performing eyelid surgery, orbital surgery, lacrimal surgery, eye socket surgery, cosmetic eye surgery, ptosis surgery, blepharoplasty, ocular oncology surgery for skin cancers like basal cell carcinoma & eye socket surgery. <br /> <br />Eyelid surgery consists of reconstructive surgery such as ptosis surgery for drooping eyelids, entropion & ectropion surgery for eyelid malpositions like entropion & ectropion, blepharoplasty surgery for eyelid bags & eyelid sagging, asian blepharoplasty surgery, blepharophimosis syndrome, telecanthus, epicanthus inversus & others. <br /> <br />Orbital surgery includes orbital decompression surgery for thyroid eye disease, orbitotomy surgery for orbital tumors like cavernous hemangioma & orbital lymphoma & orbital fracture & trauma surgery. <br /> <br />Ptosis surgery is performed for droopy eyes & is performed for both acquired, aponeurotic ptosis as well as for congenital blepharoptosis. <br /> <br />Blepharoplasty is performed to remove eyelid bags & sagging, under eye dark circles & tear trough deformities - All to create beautiful eyes. <br /> <br />Lacrimal surgery is performed to remove problems related to excessive watering of eyes, dacryocystorhinostomy (DCR surgery), dacryocystectomy, canaliculo-dacryo-cysto-rhinostomy (CDCR), tear duct blockage, recurrent eye infections, discharge from eye, etc. <br /> <br />Eye socket surgery is performed to treat anophthalmic sockets. Surgery like enucleation, evisceration, dermis fat grafts, socket reconstruction are performed and then artificial eye or ocular prosthesis can be inserted, to make sure no one realises you do not have an eye. <br /> <br />Oculo-facial plastic surgery also deals with cosmetic procedures like Botox, dermal filler injections, fat grafting, liposuction, mid-face lift, chin & cheek implants & laser skin rejuvenation treatments. <br /> <br />Ocular oncology deals with all tumors in and around the eyes, namely, skin cancers like basal cell cancer, sebaceous gland carcinoma, melanoma & squamous cell carcinoma. Eye cancer treatment also involves treatment of choroidal melanoma, retinoblastoma, retinal tumors, etc. <br /> <br />Dr. Debraj Shome is a one of the best oculoplastic surgeons in the world & currently practices in Mumbai, India. Dr. Debraj Shome is super-specialty trained in oculoplastic surgery, facial plastic surgery, maxillo-facial surgery & head & neck surgery, from the US, Europe, Singapore & India. Dr. Shome currently practices at some of the top hospitals in Mumbai, India. You will realize the difference which oculoplastic surgery creates, once you see the photos, video and results of oculopalstic surgery performed by Dr. Debraj Shome. Costs of oculoplastic surgery, ptosis surgery, eyelid surgery, blepharoplas

What Is Liver Cancer
What Is Liver Cancer administrator 4 Views • 2 years ago

What Is Liver Cancer?<br />Liver cancer is a type of cancer that starts in the liver. Cancer starts when cells in the body begin to grow out of control. To learn more about how cancers start and spread, see What Is Cancer?<br /><br />To understand liver cancer, it helps to know about the normal structure and function of the liver.<br /><br />The liver<br />The liver is the largest internal organ. It lies under your right ribs just beneath your right lung. It has two lobes (sections).<br /><br /><br />illustration showing the right and left lobes of the liver in relation to the hepatic bile duct, pancreas, gallbladder and small intestine with a detailed view of liver lobule, hepacytes (liver cells), sinusoid, canaliculus, portal vein, hepatic artery, bile duct and central vein<br />The liver is made up mainly of cells called hepatocytes. It also has other types of cells, including cells that line its blood vessels and cells that line small tubes in the liver called bile ducts. The bile ducts carry bile from the liver to the gallbladder or directly to the intestines.<br /><br />You cannot live without your liver. It has many important functions:<br /><br />It breaks down and stores many of the nutrients absorbed from the intestine that your body needs to function. Some nutrients must be changed (metabolized) in the liver before they can be used for energy or to build and repair body tissues.<br />It makes most of the clotting factors that keep you from bleeding too much when you are cut or injured.<br />It delivers bile into the intestines to help absorb nutrients (especially fats).<br />It breaks down alcohol, drugs, and toxic wastes in the blood, which then p**** from the body through urine and stool<br />The different types of cells in the liver can form several types of malignant (cancerous) and benign (non-cancerous) tumors. These tumors have different causes, are treated differently, and have a different prognosis (outlook).<br /><br />Primary liver cancer<br />A cancer that starts in the liver is called primary liver cancer. There is more than one kind of primary liver cancer.<br /><br />Hepatocellular carcinoma (HCC)<br />This is the most common form of liver cancer in adults.<br /><br />Hepatocellular cancers can have different growth patterns:<br /><br />Some begin as a single tumor that grows larger. Only late in the disease does it spread to other parts of the liver.<br />A second type seems to start as many small cancer nodules throughout the liver, not just a single tumor. This is seen most often in people with cirrhosis (chronic liver damage) and is the most common pattern seen in the United States.<br />Doctors can cl****ify several subtypes of HCC. Most often these subtypes do not affect treatment or prognosis (outlook). But one of these subtypes, fibrolamellar, is important to recognize. It is rare, making up less than 1% of HCCs and is most often seen in women younger than age 35. Often the rest of the liver is not diseased. This subtype tends to have a better outlook than other forms of HCC.<br /><br />Most of the rest of this content refers only to hepatocellular carcinoma and is called

What Is Lung Cancer
What Is Lung Cancer administrator 1 Views • 2 years ago

https://www.cancer.org/cancer/lung-cancer/about.html<br /><br />What Is Lung Cancer?<br /><br />Lung cancer is a type of cancer that starts in the lungs. Cancer starts when cells in the body begin to grow out of control. To learn more about how cancers start and spread, see What Is Cancer?<br /><br />Normal structure and function of the lungs<br /><br />Your lungs are 2 sponge-like organs in your chest. Your right lung has 3 sections, called lobes. Your left lung has 2 lobes. The left lung is smaller because the heart takes up more room on that side of the body.<br /><br />When you breathe in, air enters through your mouth or nose and goes into your lungs through the trachea (windpipe). The trachea divides into tubes called bronchi, which enter the lungs and divide into smaller bronchi. These divide to form smaller branches called bronchioles. At the end of the bronchioles are tiny air sacs known as alveoli.<br /><br />The alveoli absorb oxygen into your blood from the inhaled air and remove carbon dioxide from the blood when you exhale. Taking in oxygen and getting rid of carbon dioxide are your lungs’ main functions.<br /><br />Lung cancers typically start in the cells lining the bronchi and parts of the lung such as the bronchioles or alveoli.<br /><br />A thin lining layer called the pleura surrounds the lungs. The pleura protects your lungs and helps them slide back and forth against the chest wall as they expand and contract during breathing.<br /><br />Below the lungs, a thin, dome-shaped muscle called the diaphragm separates the chest from the abdomen. When you breathe, the diaphragm moves up and down, forcing air in and out of the lungs.<br /><br />Types of lung cancer<br /><br />There are 2 main types of lung cancer and they are treated very differently.<br /><br />Non-small cell lung cancer (NSCLC)<br /><br />About 80% to 85% of lung cancers are NSCLC. The main subtypes of NSCLC are adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. These subtypes, which start from different types of lung cells are grouped together as NSCLC because their treatment and prognoses (outlook) are often similar.<br /><br />Adenocarcinoma: Adenocarcinomas start in the cells that would normally secrete substances such as mucus.<br /><br />This type of lung cancer occurs mainly in current or former smokers, but it is also the most common type of lung cancer seen in non-smokers. It is more common in women than in men, and it is more likely to occur in younger people than other types of lung cancer.<br /><br />Adenocarcinoma is usually found in the outer parts of the lung and is more likely to be found before it has spread.<br /><br />People with a type of adenocarcinoma called adenocarcinoma in situ (previously called bronchioloalveolar carcinoma) tend to have a better outlook than those with other types of lung cancer.<br /><br />Squamous cell carcinoma: Squamous cell carcinomas start in squamous cells, which are flat cells that line the inside of the airways in the lungs. They are often linked to a history of smoking and tend to be found in the central part of the lungs, near a main airway (bronchus).<br />

Video cos'è la cheratosi attinica, la terapia è in gel- prof. G. Girolomoni, Verona
Video cos'è la cheratosi attinica, la terapia è in gel- prof. G. Girolomoni, Verona administrator 3 Views • 2 years ago

Intervista al prof. Giampiero Girolomoni, Professore ordinario di Dermatologia e Direttore della Clinica Dermatologica dell’Università degli studi di Verona. <br />Una cura innovativa per il trattamento dei tumori cutanei, un ciclo di terapia di due o tre giorni con un’unica somministrazione topica quotidiana, per trattare rapidamente le lesioni da cheratosi attinica, malattia della cute di cui soffrono milioni di persone in Italia e nel mondo. <br /> <br /> <br /> <br />Arriva in Italia Picato®, gel a base di ingenolo mebutato, frutto dell’impegno di LEO Pharma, azienda farmaceutica danese leader in Dermatologia. <br /> <br />La cheratosi attinica, patologia cutanea la cui prevalenza è in costante aumento e con un’incidenza variabile a seconda della presenza di uno o più fattori di rischio (esposizione prolungata al sole, storia di ustioni solari, fototipo chiaro, segni di danno solare, pregressi tumori cutanei) è ancora poco conosciuta e sotto-diagnosticata nonostante le lesioni possano progredire nel più frequente tumore della pelle non-melanoma, ovvero il carcinoma squamocellulare invasivo (SCC). La sua prevalenza varia tra l’11 e il 25% e arriva fino al 60%, negli adulti sopra i 40 anni nella popolazione dell’emisfero sud (Stockfleth et al., EJD 2008). In Italia è stimata attorno all’1,4% dopo i 45 anni (Naldi et al., Arch. Dermatol. 2006). <br /> <br />Chi è affetto da cheratosi attinica ha una probabilità 10 volte maggiore di sviluppare un tumore della pelle nei 12 mesi successivi se paragonato al resto della popolazione (Wolf et al., Int. J. Dermatol. 2013); i pazienti oltre i 65 anni hanno un rischio 6 volte superiore di sviluppare un carcinoma cutaneo rispetto a chi non è affetto da cheratosi attinica (Traianou et al., BJD 2012). La principale causa di cheratosi attinica è la radiazione UVB dei raggi solari che induce una mutazione specifica del DNA cellulare. <br /> <br />«La cheratosi attinica è una forma di carcinoma allo stadio iniziale o “in situ”; le lesioni attiniche sono molto antiestetiche e ciascuna potenzialmente pericolosa perché a rischio di evoluzione maligna», afferma Giampiero Girolomoni, Professore ordinario di Dermatologia e Direttore della Clinica Dermatologica dell’Università degli studi di Verona. «Non è possibile prevedere quale e quando una delle numerose lesioni andrà incontro a una progressione in carcinoma squamoso cellulare, tumore maligno che richiede una diagnosi precoce e un trattamento adeguato di tutte le lesioni». <br /> <br />http://www.salutedomani.com/il...._weblog_di_antonio/2

Lauren Miller - Hearing His Whisper: A Journey through ...
Lauren Miller - Hearing His Whisper: A Journey through ... administrator 4 Views • 2 years ago

For more info on this and other stories, visit www.newsinfusion.com Denver, CO - Lauren Miller is a survivor, in every sense of the word. On January 10, 2006, two weeks prior to her final divorce court date, the mother of three children, second degree black belt, fitness trainer, inspirational speaker and teacher, was diagnosed with stage three breast cancer: invasive ductal carcinoma grade three. She was given a 50 percent chance of survival because of her age and the advanced stage of her cancer. In her first book Hearing His Whisper, Lauren Miller shares her remarkable story of hope and perseverance in the midst of cancer and divorce. “I tell people it’s not about what you do in life, but about who you are in relation to God and others,” says Miller. “You can’t always help what happens in life when it comes to life and death, but you can choose how to respond to your circumstances.”

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