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Today, CancerBro will explain esophageal or esophagus cancer staging. <br /><br />Video Transcript:<br /><br />The staging system used for esophageal cancer is known as TNM staging system. <br /><br />This diagram is a magnified image of cross-sectiob of wall of esophagusm. Imagine the upper part is the inner side and lower part is outer side. <br /><br />The innermost layer is called as epithelium, followed by this layer, called as lamina propria.<br /><br />Outer to the lamina propria, is this layer called as muscularis mucosa. <br /><br />Outer to which, lies this layer which is called as submucosa. Then lies muscularis propria. <br /><br />And on the outermost aspect, lies this layer which is called as serosa or adven****ia. <br /><br />Now, let's discuss the T-staging for esophageal cancer. <br /><br />First is Tis, or carcinoma in situ. This is not considered malignant, and is localised to epithelium.<br /><br />Infiltration of lamina propria or muscularis mucosa is called as T1a disease. <br /><br />Infiltration into submucosa is called as T1b. Muscularis propria infiltration is called as T2. And infiltration of serosa or adven****ia is called as T3. <br /><br />Till T3 disease, the cancer is limited to the wall of esophagus, and does not extend outside to involve adjacent structures. <br /><br />Whereas in T4 disease, the cancer infiltrates through the wall of esophagus and involves adjacent structures, like in this figure, the cancer has infiltrated into the heart or pericardium.<br /><br />And here, it has infiltrated into the lungs or pleora. And here it infiltrates the diaphragm. It may also infiltrate anteriorly, into the trachea. Or into the great vessels of heart. <br /><br />So this finishes the T-stage, now let's come to the N-stage. <br /><br />N staging maybe N1, N2 or N3, depending upon the number of lymph nodes involved. <br /><br />Last comes the M or the metastatic staging, which determines the spread of cancer to distance sites. Like in this figure, the cancer has spread to involve both the lungs. And here it has spread to the liver in form of multiple nodular deposits. <br /><br />Rarely, the cancer may spread to bones.<br /><br />So this completes the TNM staging for esophageal cancer. <br /><br />CancerBro is also active on most social media channels. Follow him to get rich and authoritative content related to cancer awareness, risk factors, symptoms, diagnosis, treatment, etc. <br /><br />Facebook - https://www.facebook.com/officialcancerbro<br />Instagram - https://www.instagram.com/official_cancerbro<br />Twitter - https://twitter.com/cancer_bro/<br />Website - http://www.cancerbro.com/

Watch this video to know what are the various stages of stomach cancer. <br /><br />Video Transcript:<br /><br />Now, after discussing the different layers of stomach wall, let's discuss the T-staging of the stomach cancer.<br /><br />First is the Tis ot carcinoma in situ. This is not considered as malignant, and is localised to epithelium. <br /><br />Infiltration of lamina propria or muscularis mucosa is called as T1a disease. <br /><br />Infiltration into the submucosa is called as T1b. Muscularis propria infiltration is called as T2. <br /><br />Infiltration of subserosa is called as T3. And infiltration of the tumor into the serosa is called as T4a disease. <br /><br />When the tumor extends through the stomach walls to involve the adjacent structures it is called as T4b. <br /><br />In this figure the tumor extends to involve the colon. And here it infiltrates the pancreas. And here the tumor infiltrates into the spleen. And here it invades the kidney. It may also infiltrate into the liver or the diaphragm.<br /><br />This finishes the T staging of the stomach cancer, now next comes the N staging or the nodal staging. <br /><br />The regional nodes which drain the stomach are different in different part of stomach. <br /><br />These nodes drain the lesser curvature of the stomach. And these drain the upper part of the greater curvature of the stomach. And these the lower part. <br /><br />These nodes drain the pyloric antrum. All the nodes draining the different part of the stomach, ultimately drain into these nodes which is called as the coeliac nodes. <br /><br />M staging refers to the distance spread of the tumor to different parts of the body.<br /><br />DistanT metastasis maybe seen to the liver. The peritoneum in form of multiple peritoneal deposits. <br /><br />To the lungs in form of multiple nodular deposits. Rarely, it may spread to the left supraclavicular lymph node which presents as nodular deposits in the left side of the neck.<br /><br />Or a nodular deposit in the periumbilical region, called as sister Mary Joseph nodule. <br /><br />It may also present as pelvic deposits in the rectovesical pouch or pouch of douglas. <br /><br />Or as nodular deposits in one or both the ovaries, called as Krukenberg's tumor. Very rarely, it may also spread to brain or bones. <br /><br />This finishes the TNM staging for stomach cancer. <br /><br />CancerBro is also active on social media channels. Follow him to get rich and authoritative content related to cancer awareness, risk factors, symptoms, diagnosis, treatment, etc. <br /><br />Facebook - https://www.facebook.com/officialcancerbro<br />Instagram - https://www.instagram.com/official_cancerbro<br />Twitter - https://twitter.com/cancer_bro/<br />Website - http://www.cancerbro.com/

Most of the time, treatment of bladder cancer is based on the tumor’s clinical stage when it's first diagnosed. This includes how deep it's thought to have grown into the bladder wall and whether it has spread beyond the bladder. Other factors, such as the size of the tumor, how fast the cancer cells are growing (grade), and a person’s overall health and preferences, also affect treatment options.<br /><br />Treating stage 0 bladder cancer<br />Stage 0 bladder cancer includes non-invasive papillary carcinoma (Ta) and flat non-invasive carcinoma (Tis or carcinoma in situ). In either case, the cancer is only in the inner lining layer of the bladder. It has not invaded (spread deeper into) the bladder wall.<br /><br />This early stage of bladder cancer is most often treated with transurethral resection (TURBT) with fulguration followed by intravesical therapy within 24 hours.<br /><br />Stage 0a<br />Sometimes no further treatment is needed. Cystoscopy is then done every 3 to 6 months to watch for signs that the cancer has come back.<br /><br />For low-grade (slow-growing) non-invasive papillary (Ta) tumors, weekly intravesical chemotherapy may be started a few weeks after surgery. If the cancer comes back, the treatments can be repeated. Sometimes intravesical chemo is repeated over the next year to try to keep the cancer from coming back.<br /><br />High-grade (fast-growing) non-invasive papillary (Ta) tumors are more likely to come back after treatment, so intravesical BCG is often used after surgery. Before it's given, TURBT is commonly repeated to be sure the cancer has not affected the muscle layer. BCG is usually started a few weeks after surgery and is given every week for several weeks. Intravesical BCG seems to be better than intravesical chemotherapy for high-grade cancers. It can help both keep these cancers from coming back and keep them from getting worse. But it also tends to have more side effects. It, too, may be done for the next year or so.<br /><br />Stage 0 bladder cancers rarely need to be treated with more extensive surgery. Partial or complete cystectomy (removal of the bladder) is considered only when there are many superficial cancers or when cancer continues to grow (or seems to be spreading) despite treatment.<br /><br />Stage 0is<br />For flat non-invasive (Tis) tumors, intravesical BCG is the treatment of choice after TURBT. Patients with these tumors often get 6 weekly treatments of BCG, starting a few weeks after TURBT. Some doctors recommend repeating BCG treatment every 3 to 6 months.<br /><br />Follow-up and outlook after treatment<br />After treatment for any stage 0 cancer, close follow-up is needed, with cystoscopy about every 3 months for a least a couple of years to look for signs of the cancer coming back or new bladder tumors.<br /><br />The outlook for people with stage 0a (non-invasive papillary) bladder cancer is very good. These cancers can be cured with treatment. During long-term follow-up care, more superficial cancers are often found in the bladder or in other parts of t

Treatment Options for Oral Cavity and Oropharyngeal Cancer by Stage<br />This information is based on AJCC Staging systems prior to 2018 which were primarily based on tumor size and lymph node status. Since the updated staging system for oropharyngeal cancer now also includes the p16 status of the tumor, the stages may be higher or lower than previous staging systems. Whether or not treatment strategies will change with this new staging system are yet to be determined. You should discuss your stage and treatment options with your physician. <br /><br />The type of treatment your doctor will recommend depends on where the tumor is and how far the cancer has spread. Here are common ways to treat different stages of oral cavity and oropharyngeal cancer. But each situation is different. Your doctor may have reasons for suggesting a treatment option not mentioned here.<br /><br />Most experts agree that treatment in a clinical trial should be considered for any type or stage of cancer in the head and neck areas. This way people can get the best treatment available now and may also get the new treatments that are thought to be even better.<br /><br />Stage 0 (carcinoma in situ)<br />Although cancer in this stage is on the surface layer and has not started to grow into deeper layers of tissue, it can do so if not treated. The usual treatment is surgery (usually Mohs surgery, surgical stripping, or thin resection) to remove the top layers of tissue along with a small margin (edge) of normal tissue. Close follow-up is important to watch for signs that the cancer has come back. Carcinoma in situ that keeps coming back after surgery may need to be treated with radiation therapy.<br /><br />Nearly all people with this stage survive a long time without the need for more intense treatment. Still, it's important to note that continuing to smoke increases the risk that a new cancer will develop.<br /><br />Stages I and II<br />Most patients with stage I or II oral cavity and oropharyngeal cancer do well when treated with surgery and/or radiation therapy. Chemotherapy (chemo) given along with radiation (called chemoradiation) is another option. It can be used alone, but it's most often used after surgery to treat any cancer cells that may be left behind. Both surgery and radiation work well in treating these cancers. The choice depends on your preferences and the expected side effects, including how the treatment might affect how you look and how you swallow and speak.<br /><br />Lip<br />Surgery is preferred for small cancers that can be removed. Radiation alone may also be used as the first treatment. In this case, surgery might be needed later if radiation doesn’t completely get rid of the tumor.<br /><br />Large or deep cancers often require surgery. If needed, reconstructive surgery can help correct the defect in the lip.<br /><br />If the tumor is thick, it increases the risk that the cancer might have spread to lymph nodes in the neck, so the surgeon may remove them (called lymph node dissection) so they can be checked for cancer spread.<br />

Intervista al prof. Giampiero Girolomoni, Professore ordinario di Dermatologia e Direttore della Clinica Dermatologica dell’Università degli studi di Verona. <br />Una cura innovativa per il trattamento dei tumori cutanei, un ciclo di terapia di due o tre giorni con un’unica somministrazione topica quotidiana, per trattare rapidamente le lesioni da cheratosi attinica, malattia della cute di cui soffrono milioni di persone in Italia e nel mondo. <br /> <br /> <br /> <br />Arriva in Italia Picato®, gel a base di ingenolo mebutato, frutto dell’impegno di LEO Pharma, azienda farmaceutica danese leader in Dermatologia. <br /> <br />La cheratosi attinica, patologia cutanea la cui prevalenza è in costante aumento e con un’incidenza variabile a seconda della presenza di uno o più fattori di rischio (esposizione prolungata al sole, storia di ustioni solari, fototipo chiaro, segni di danno solare, pregressi tumori cutanei) è ancora poco conosciuta e sotto-diagnosticata nonostante le lesioni possano progredire nel più frequente tumore della pelle non-melanoma, ovvero il carcinoma squamocellulare invasivo (SCC). La sua prevalenza varia tra l’11 e il 25% e arriva fino al 60%, negli adulti sopra i 40 anni nella popolazione dell’emisfero sud (Stockfleth et al., EJD 2008). In Italia è stimata attorno all’1,4% dopo i 45 anni (Naldi et al., Arch. Dermatol. 2006). <br /> <br />Chi è affetto da cheratosi attinica ha una probabilità 10 volte maggiore di sviluppare un tumore della pelle nei 12 mesi successivi se paragonato al resto della popolazione (Wolf et al., Int. J. Dermatol. 2013); i pazienti oltre i 65 anni hanno un rischio 6 volte superiore di sviluppare un carcinoma cutaneo rispetto a chi non è affetto da cheratosi attinica (Traianou et al., BJD 2012). La principale causa di cheratosi attinica è la radiazione UVB dei raggi solari che induce una mutazione specifica del DNA cellulare. <br /> <br />«La cheratosi attinica è una forma di carcinoma allo stadio iniziale o “in situ”; le lesioni attiniche sono molto antiestetiche e ciascuna potenzialmente pericolosa perché a rischio di evoluzione maligna», afferma Giampiero Girolomoni, Professore ordinario di Dermatologia e Direttore della Clinica Dermatologica dell’Università degli studi di Verona. «Non è possibile prevedere quale e quando una delle numerose lesioni andrà incontro a una progressione in carcinoma squamoso cellulare, tumore maligno che richiede una diagnosi precoce e un trattamento adeguato di tutte le lesioni». <br /> <br />http://www.salutedomani.com/il...._weblog_di_antonio/2

For more info on this and other stories, visit www.newsinfusion.com Denver, CO - Lauren Miller is a survivor, in every sense of the word. On January 10, 2006, two weeks prior to her final divorce court date, the mother of three children, second degree black belt, fitness trainer, inspirational speaker and teacher, was diagnosed with stage three breast cancer: invasive ductal carcinoma grade three. She was given a 50 percent chance of survival because of her age and the advanced stage of her cancer. In her first book Hearing His Whisper, Lauren Miller shares her remarkable story of hope and perseverance in the midst of cancer and divorce. “I tell people it’s not about what you do in life, but about who you are in relation to God and others,” says Miller. “You can’t always help what happens in life when it comes to life and death, but you can choose how to respond to your circumstances.”