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Alright...today, we will go over some common classes of drugs used in treating cancer and examples within each class. To remind you of this, this picture is a scene out of the latest sci-fi movie starring my main man...VIN EASEL. The plot?...Vin Easel and his crew battling a giant cancer crab.
Vinca alkaloids: Vinblastine, Vincristine
First up, are the Vinca alkaloids represented by Vin Easel. VIN BLASTING the crab is VINBLASTINE, and VIN with the CROSS is VINCRISTINE.
Antimetabolites - Methotrexate, Fluorouracil, Mercaptopurine
Next, we have the antimetabolites, represented by the T-Rex. The METH smoking T-REX is METH-O-TREX-ATE, his FLORAL shorts is FLUORO-URACIL, and his MERCEDES CAP is MER-CAP-TOPURINE. *we do not condone smoking meth*
Taxanes: Paclitaxel
Another class are the Taxanes, represented by the Tax Man. He’s is wearing a PACK of TAXES, which is PAC-LITAXEL.
Alkylating Agents - Cyclophosphamide, Carboplatin, Cisplatin, Busulfan
Lastly, we have the Alkylating agents, these are represented by the vehicles in the back line. The CYCLONE CYCLER on his PHOSPHATE bike is CYCLOPHOSPHAMIDE. The CAR of PLATINUM is CARBOPLATIN, and his SISter car is CIS-PLATIN. The BUS wielding FANS is BUS-UL-FAN.
Alright folks, that’s it for this video! To learn more about visual mnemonics and Cancer drugs, including mechanisms of action and side effects, please check out our website at VisualLearner.net. Happy studying!
Study this Vincristine NCLEX mnemonic and other mnemonics with Pixorize.
Vincristine and vinblastine are chemotherapy agents used to treat a variety of cancers. They are antimicrotubules agents, which means that they work by inhibiting the function of microtubules. Both drugs cause generic side effects seen with all chemotherapies like bone marrow suppression and GI upset. More specific to vincristine and vinblastine is the finding of neurotoxicity, and any neurological symptoms should be reported to the provider.
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Video lectures in Clin Pharmacol
Prof AM Fouda
The PDF file of this lecture is found here:
https://drive.google.com/file/....d/1NWlWvDQDLlHZGpf0B
-------- Contents of this video -------------------
00:00 - Classifications
02:20 - Adverse effects of ACDs
05:42 - Alkylating agents
07:33 - MOA
11:47 - cyclophosphamide
19:40 - Cisplatin
24:23 - Antimetabolites
25:52 - MOA of Methotrexate
27:00 - MOA of 6-mercaptopurine
28:25 - MOA of 5-fluorouracil
29:21 - Methotrexate
35:06 - 6-mercaptopurine min
40:40 - Cytotoxic antibiotics
Cancer drugs Side effects (Chemo toxicities) - Visual mnemonic / Anticancer drug mnemonic / Remember anticancer drugs side effects
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Video lecture in Arabic: Pathophysiology and key concepts of cancer
Dr AM Fouda, MD, PhD
Professor of Clin Pharmacology
Mansoura University Faculty of Medicine, Egypt
Link to the PDF file:
https://drive.google.com/file/....d/1NWlWvDQDLlHZGpf0B
-------- Contents of this video -------------------
00:00 - Introduction
03:36 - The hallmarks of cancer
11:16 - Proliferation, differentiation and undifferentiation
16:22 - The cell cycle
23:30 - Checkpoints
25:55 - Cell cycle regulators
36:05 - Cancer genetics
36:40 - Tumor suppressor genes
37:45 - Proto- oncogenes
40:05 - Growth factors & uncontrolled Proliferation
46:26 - Cancer signaling network
48:12 - The telomere & telomerase
58:36 - Cancer therapeutic options
