32-year-old female marathon runner who presented with uncontrolled hypertension and recurrent episodes of vertigo. A series of contrast enhanced MRA images of the neck are provided demonstrating a circumscribed, solid appearing, avidly enhancing masses. There are lesions involving the prevascular space between the left common carotid and subclavian arteries, more superiorly at the level of the left carotid bifurcation, with additional subcentimeter lesions along the left and right internal carotid arteries. The largest lesions demonstrate prominent internal vessels. On the time of flight MRA of the neck, prominent flow voids were identified within the lesions. The 3-D maximal intensity projection MRA image demonstrates the left carotid bifurcation lesion nicely. The findings are compatible with multiple paragangliomas. The patient was given a diagnosis of multiple hereditary paraganglioma and pheochromocytoma syndrome. Paraganglioma may also be seen in the setting of VHL, MEN-2, NF-1, mitochondrial succinate dehydrogenase mutations, tuberous sclerosis, Carney triad and Sturge-Weber. NMR224

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Lesson on Pheochromocytoma: Symptoms and Treatment. Pheochromocytoma is a medical condition caused by a catecholamine-secreting tumor formed by chromaffin cells within the adrenal medulla. This tumor secretes excessive amounts of catecholamines, leading to a variety of symptoms including hypertension, a pounding headache and tachycardia. Pheochromocytoma has a similar presentation to a paraganglioma, which originates from sympathetic nervous tissue as opposed to pheochromocytoma. However, both pheochromocytoma and paragangliomas are managed and treated similarly, so often are categorized together.

Pheochromocytoma is often idiopathic, but can be associated with a variety of genetic conditions including MEN2. Diagnosis of pheochromocytoma involves measuring catecholamine levels and catecholamine breakdown products known as metanephrines in the plasma . When pheochromocytoma has been diagnosed, surgery is often required in order to resect the tumor; however, careful treatment and management is required prior to surgery for successful outcomes. I hope you find this video helpful. If you do, please like and subscribe for more videos like this one :)

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PHEOCHROMOCYTOMA is a catecholamine secreting tumor of the adrenal gland originating from the chromaffin cells), or extra-adrenal chromaffin tissue that failed to involute after birth that secretes high amounts of catecholamines, mostly norepinephrine, plus epinephrine to a lesser extent.

Extra-adrenal paragangliomas (often described as extra-adrenal pheochromocytomas) are closely related, though less common,

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Lisa Kozempel Erdely tells the story of her mother's struggle before being diagnosed with pheochromocytoma.

Visit www.pheoparatroopers.org for more information on pheos and paras, and how you can help fight this cancer.

You can also support rare disease by donating to Lori Kozempel's Memorial Fund:

https://salsa3.salsalabs.com/o..../…/donate_pa…/resear

Please select “Pheochromocytoma” on the research fund drop down select option. Then Click “Dedicate my donation to Lori Kozempel.” To donate by mail, please send a check to the NORD Connecticut office:

National Organization for Rare Disorders
55 Kenosia Avenue
Danbury, CT 06810

Or to donate by phone, please call to Mary Talbot who is an Accountant at NORD:

(617) 934-6387

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No two cancers are the same, nor are they treated the same, and neither should nutrition be the same for everyone. Nutrition includes foods like pulses, vegetables, fruits, nuts, oils, herbs and spices. Also nutrition includes supplements which are high concentrations of foods or high concentrations of individual ingredients found in foods. For cancers like Pheochromocytoma And Paraganglioma when undergoing chemotherapy or when you determine you have a genetic risk for developing Pheochromocytoma And Paraganglioma because of EPAS1 and AWAT1 gene mutations, a very important question is “What foods should I avoid and what foods are recommended specifically for me?”. The other related question is “What nutritional supplements should I avoid?”.

There is no one answer to this question for cancers such as Pheochromocytoma And Paraganglioma which can be found through internet searches. The answer to the question is “It Depends” because the nutrition plan needs to be personalized for you. Nutrition should depend on the cancer indication, genetic information, adult or pediatric, staging, primary or secondary, advanced, metastatic, relapsed or refractory, ongoing treatments if any, nutritional supplements being taken, age and factors like gender, weight, height, lifestyle, allergies and food preferences.

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When Jagdish, a person with a history of hypertension, started to feel chronic back pain, he was told that muscle relaxants will help his situation. After a lot of struggle and no results, he visited Manipal Hospitals, Old Airport Road where a team of multidisciplinary doctors diagnosed him with a rare tumour called Paraganglioma. After a successful surgery, he is now on the road to recovery!

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Best Hospital in India: Manipal Hospitals is one of the top multi-specialty hospital in India located at all major cities like Bangalore, Vijayawada, Visakhapatnam, Goa, Salem, Jaipur, Mangalore. It provides world-class 24/7 Emergency services. Our top surgeons are experts in offering the best treatment for Heart, Brain, Cancer, Eye, Kidney, Joint & all major surgeries at affordable costs. Health Check up packages are also available.

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