Pheochromocytoma: Symptoms, Pathophysiology, Diagnosis and Treatment

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07/02/23

Lesson on Pheochromocytoma: Symptoms and Treatment. Pheochromocytoma is a medical condition caused by a catecholamine-secreting tumor formed by chromaffin cells within the adrenal medulla. This tumor secretes excessive amounts of catecholamines, leading to a variety of symptoms including hypertension, a pounding headache and tachycardia. Pheochromocytoma has a similar presentation to a paraganglioma, which originates from sympathetic nervous tissue as opposed to pheochromocytoma. However, both pheochromocytoma and paragangliomas are managed and treated similarly, so often are categorized together.

Pheochromocytoma is often idiopathic, but can be associated with a variety of genetic conditions including MEN2. Diagnosis of pheochromocytoma involves measuring catecholamine levels and catecholamine breakdown products known as metanephrines in the plasma . When pheochromocytoma has been diagnosed, surgery is often required in order to resect the tumor; however, careful treatment and management is required prior to surgery for successful outcomes. I hope you find this video helpful. If you do, please like and subscribe for more videos like this one :)

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