The Genetic Basis of Kidney Cancer: Targeting the Metabolic Basis of Disease

The Genetic Basis of Kidney Cancer: Targeting the Metabolic Basis of Disease

Air date: Wednesday, November 20, 2013, 3:00:00 PM

Runtime: 01:05:55

Description:

NIH Wednesday Afternoon Lecture

Annual Astute Clinican Lecture

Dr. Linehan has had a long-standing interest in identification of the genetic basis of cancer of the kidney. Kidney cancer is not a single disease. It is made up of a number of different types of cancer, each of which has a different histology, a different clinical course, which respond differently to therapy and are caused by different genes. Studies of the kidney cancer gene pathways have revealed that kidney cancer is fundamentally a metabolic disease. These findings have provided the foundation for the development of targeted therapeutic approaches for patients with advanced forms of this disease.

The annual Astute Clinician lecture within the NIH Director's Wednesday Afternoon Lecture Series (WALS) highlights exciting clinical observations that have served as a focus for research. This series has been made possible through the generous gift of the late Dr. Robert W. Miller, Scientist Emeritus, National Cancer Institute and his wife, Haruko (Holly) Miller.

For more information go to http://wals.od.nih.gov

Author: Dr. Marston Linehan, Chief, Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH

Permanent link: http://videocast.nih.gov/launch.asp?18182