Should we delay transplantation in patients with standard-risk multiple myeloma?

Paul Richardson, MD, Dana-Farber Cancer Institute, Boston, MA, comments on changes in the use of stem cell transplantation (SCT) as a frontline therapy for younger, standard-risk, transplant-eligible patients with multiple myeloma. Dr Richardson discusses results from the DETERMINATION Phase III clinical trial (NCT01208662) which has demonstrated that overall survival (OS) outcomes are comparable across groups of patients undergoing early versus late transplant. Dr Richardson further highlights advantages and disadvantages of delaying SCT in certain patient populations, and explains the importance of having access to novel agents. This interview took place at the 9th World Congress on Controversies in Multiple Myeloma (COMy) 2023, held in Paris, France.

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