PI3K and PARP Inhibitors in HR+ Metastatic Breast Cancer

Joyce A. O’Shaughnessy, MD, and Andrew D. Seidman, MD, evaluate treatment options outside of CDK4/6 inhibition, such as PI3-kinase or poly(adenosine diphosphate–ribose) polymerase (PARP) inhibitors, for patients with hormone-receptor positive metastatic breast cancer.

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