NF1 Panel Discussion On MPNST Biomarkers
People with neurofibromatosis type 1, or NF1, often develop non-cancerous (benign) tumors that grow along nerves. These tumors can sometimes turn into aggressive cancers (i.e., MPNST), but there hasn't been an ideal way to monitor whether this transformation to cancer has started. Finding cancer early leads to earlier treatment and better health outcomes, so improving our ability to detect malignancy could save lives. In this webinar, top experts in the field will explain their research into new approaches to detect cancer in NF1 and answer your questions about what this could mean for you and your family.
Today, doctors use scans (MRI or PET) or biopsies to diagnose MPNST. However, biopsy findings aren't always accurate, and the procedure can be painful. Scans, especially whole-body MRI, are also used to diagnose MPNST, but they involve contrast agents that can cause side effects. In addition, MRIs are expensive, not suitable for all, and may not lead to a definite diagnosis.
With advancements in genomics, radiography, and artificial intelligence (AI), more and more research groups are exploring new approaches that offer a highly sensitive and inexpensive method to detect signs of transformation to cancer in its earliest stages. From ”liquid biopsies” based on blood tests to AI-enhanced imaging, they have shown the promise of these technologies to be more effective for early diagnosis and monitoring treatment response.
Moderated panel:
Elizabeth O’Brien Burke, Patient Advocate, member CureNFwith Jack
Brigitte Widemann, MD, National Cancer Institute
Taylor Sundby, MD Advanced Fellow in Pediatric Hematology/Oncology at NCI (TBC)
Raymond Kim, MD, Ph.D. University Health Network, Toronto
Ping Chi, MD, Ph.D. Memorial Sloan Kettering Cancer Center
Angela Hirbe, MD, Ph.D. Washington University School of Medicine
Jonathan Karpelowsky, MD, Ph.D. Associate Professor at the University of Sydney
This video is closed-captioned. Please click the CC button above to access the captions.
Para ver este seminario web en español, vaya a: https://youtu.be/RmnVOGf9xiU
To learn more about the Children's Tumor Foundation, please visit ctf.org.
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