Lynch Syndrome

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06/29/23

Episode 43

March is Colorectal Awareness Month and March 2nd is Lynch Syndrome Awareness Day! HNPCC, more commonly known as Lynch Syndrome, is an inherited condition that greatly increases the risk of many cancers, most notably colorectal cancer. This condition also increases the risk for other cancers such as endometrial, ovarian and gastric cancers. Cancers that have a less severe risk increase include hepatobiliary tract, urinary tract, small bowel, pancreatic, brain/central nervous system and sebaceous neoplasms. Not all people with Lynch Syndrome have the same elevated risks; risk levels depend on which gene(s) have mutations. Lynch Syndrome is caused by mutations in the following genes: MLH1, MSH2, MSH6, PMS2, and/or EPCAM. In this episode, learn about the differing risks of types of cancers between genes along with how those gene variants are identified and measures that can be taken to reduce those risks!

For more information about this episode, check out our blog post here:
http://dnapodcast.com/episodes..../2016/3/21/43-lynch-

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DNA Today is a podcast and radio show exploring geneticsโ€™ impact on health through conversations with leaders in genetics like genetic counselors, researchers, doctors, and patient advocates. The show started in 2012 and features over 125 episodes. DNA Today has been nominated in the Podcast Awards in 2015, 2016 and 2019.

DNA Today is broadcast every Friday at 10:30am ET on WHUS 91.7 FM in Connecticut. New episodes are released on the first Friday of the month with some bonus episodes on other Fridays.

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