How Melanoma Develops: Causes and Pathology

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07/03/23

presented by, George Jour, MD, Clinical Associate Professor, Department of Pathology, NYU Grossman School of Medicine, Clinical Associate Professor, Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine,Director, Molecular Pathology Fellowship Program
Associate Director, Molecular Pathology Laboratory

Melanoma, the most serious type of skin cancer, develops in the cells (melanocytes) that produce melanin — the pigment that gives your skin its color. Melanoma can also form in your eyes and, rarely, inside your body, such as in your nose or throat.

The exact cause of all melanomas isn't clear, but exposure to ultraviolet (UV) radiation from sunlight or tanning lamps and beds increases your risk of developing melanoma. Limiting your exposure to UV radiation can help reduce your risk of melanoma.

The risk of melanoma seems to be increasing in people under 40, especially women. Knowing the warning signs of skin cancer can help ensure that cancerous changes are detected and treated before the cancer has spread. Melanoma can be treated successfully if it is detected early.