Familial Adenomatous Polyposis by Sarah-Jane Shaw

This podcast discusses the inherited condition known as Familial Adenomatous Polyposis characterized by the development of abnormal growths called polpys in the lining of the large intestine. It describes how a mutation in a gene (in this case the APC gene) leads to the development of this adenomas (in other words polyps) and how the inheritance of this mutation can be observed in a family and adequate early screening can be done to increase chances of survival. This inherited condition has been linked to approximately 1 in100 cases of bowel cancer.