Cervical cancer patients have lower recurrence rates with open hysterectomy

In the first randomized-controlled Phase III clinical trial to compare surgical options for women with early-stage cervical cancer, researchers at The University of Texas MD Anderson Cancer Center discovered that minimally invasive radical hysterectomy is associated with higher recurrence rates and worse overall survival compared to abdominal radical hysterectomy.

The study published in the New England Journal of Medicine was led by Pedro Ramirez, M.D., professor of Gynecologic Oncology and Reproductive Medicine at MD Anderson. The international study was a multi-institutional collaboration with 33 centers worldwide. It opened in 2008 and was designed to randomize 740 women with early-stage (I-A or 1-B) cervical cancer to undergo either minimally invasive or open radical hysterectomy.

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