ACUTE LYMPHOBLASTIC LEUKEMIA AND LYMPHOBLASTIC LYMPHOMA PROGNOSIS

Good prognosis:
Young =2-9 years
WBC less than 30 x 10 9 /L
T-cell phenotype
Absence of Philadelphia chromosome
Early attainment of complete remission
Bad prognosis:
Older kids
WBC greater than 30 x 10 9/L
B-cell phenotype
Presence of t 9:22 Philadelphia chromosome
Late attainment of complete remission
Differential Diagnosis:
AML= Acute Myeloid Leukemia
AUL= Acute Undifferentiated Leukemia
MPAL= Mixed Phenotype Acute Leukemia
CML= Chronic Myeloid Leukemia
Aplastic anemia
Burkitt lymphoma
HIV
Infections mononucleosis
Pertussis
Osteomyelitis
Thymoma
Juvenile rheumatoid arthritis
Heavy metal toxicity
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