WHAT IS GESTATIONAL TROPHOBLASTIC DISEASE (GTD)?

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06/30/23

This video is about Gestational Trophoblastic Diseases (GTD). Gestational trophoblastic disease (GTD) is a group of rare diseases in which abnormal trophoblast cells grow inside the uterus after conception. In gestational trophoblastic disease (GTD), a tumor develops inside the uterus from tissue that forms after conception (the joining of sperm and egg).GTD begins in the layer of cells called the trophoblast that normally surrounds an embryo. (Tropho- means nutrition, and -blast means bud or early developmental cell.) Early in normal development, the cells of the trophoblast form tiny, finger-like projections known as villi. The villi grow into the lining of the uterus. In time, the trophoblast layer develops into the placenta, the organ that protects and nourishes the growing fetus.
The main types of gestational trophoblastic diseases are:
Hydatidiform mole (complete or partial)
Invasive mole
Choriocarcinoma
Placental-site trophoblastic tumor
Epithelioid trophoblastic tumor

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