Visualizing viral replication of oncogenic human herpesviruses
Presented By: Lindsey M. Costantini, PhD
Speaker Biography: Dr. Costantini completed her doctorate degree in Biomedical Research at Albert Einstein College of Medicine in New York. Dr. Costantini’s research focus integrates her background in cellular and molecular biology and virology with high-resolution microscopy approaches.
Webinar: Visualizing viral replication of oncogenic human herpesviruses
Webinar Abstract: Viruses are the causative agents of approximately 12% of human cancers. The most recently discovered herpesvirus, Kaposi’s sarcoma herpesvirus (KSHV) is known to cause three human cancers. Effective antiviral therapeutics are needed for the treatment of KSHV. Viral DNA replication and the KSHV DNA replication proteins are essential to successful viral replication and, thus, appealing therapeutic targets. Our focus is characterizing the functions and molecular interactions of the core KSHV DNA replication proteins in order to develop potential therapeutic strategies against KSHV infection.
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