How To Diagnose Peritoneal Mesothelioma? - What Is Peritoneal Mesothelioma?

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07/02/23

How To Diagnose Peritoneal Mesothelioma?
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Peritoneal Mesothelioma Treatment.

Peritoneal mesothelioma is often treated with a multimodal approach, which combines conventional treatments like surgery, chemotherapy and radiation therapy.

Traditional chemotherapy and radiation therapy have shown limited success in peritoneal mesothelioma patients, with many clinical trials showing a median survival time of one year. However, some studies indicate success when using chemotherapy during surgery to treat peritoneal mesothelioma.

For patients with advanced stage peritoneal malignant mesothelioma, standard treatments may be used as palliative care. Palliative treatments are used to improve quality of life and extend life expectancy.

Minimally invasive procedures, like paracentesis, are often used palliatively. This procedure removes buildup of fluid and relieves symptoms associated with peritoneal malignant mesothelioma.

Clinical trials are continually testing new treatments for peritoneal mesothelioma. Emerging treatment options include pressurized intraperitoneal aerosol chemotherapy (PIPAC), a chemotherapy applied in a pressurized form. Treating mesothelioma with PIPAC is in early phases and requires further testing. However, the treatment has shown a median life expectancy of approximately 27 months.

Hyperthermic Intraperitoneal Chemotherapy (HIPEC).

For eligible patients, a combination treatment of debulking surgery combined with heated chemotherapy is becoming a standard of care. The heated chemotherapy, known as hyperthermic intraperitoneal chemotherapy (HIPEC), is applied to the abdomen during surgery.

Doctors perform debulking surgery, also known as cytoreductive surgery, prior to HIPEC to remove visible tumors and tissue that have been damaged by mesothelioma cells. This may involve removing the abdominal lining or other organs in order to remove as much of the tumor as possible.

HIPEC is then applied throughout the abdominal cavity to kill any remaining cancer cells. The heated chemotherapy is applied at 104°F – 109°F and consists of a stronger dosage than traditional chemotherapy.

Clinical trials have shown the effectiveness of the treatment, with life expectancy ranging from 53 to 92 months. Data suggests approximately 65% of patients survive five years or longer.

Because HIPEC is a specialized treatment, it is available at select cancer centers. Patients should also be aware of treatment costs as they make treatment decisions. Recent estimates show that surgery with HIPEC can average $40,000.

Common Questions About Peritoneal Mesothelioma.

Is peritoneal mesothelioma curable?
There is no cure for peritoneal mesothelioma. There are treatment options available that may improve life expectancy.

How long do peritoneal mesothelioma patients live?
A peritoneal mesothelioma patient has a life expectancy of two to six years depending on stage at diagnosis.

What are the symptoms of peritoneal mesothelioma?
Some common symptoms of peritoneal mesothelioma are abdominal pain, abdominal swelling, weight loss, fever, fluid in peritoneal cavity, intestinal obstruction, night sweats and hypercoagulability.

Can peritoneal mesothelioma spread to the lungs?
Yes, peritoneal mesothelioma can spread to the lungs. This process is called metastasis.

How is peritoneal mesothelioma diagnosed?
A biopsy is the only way to definitively diagnose malignant peritoneal mesothelioma. Other diagnostic tests like imaging scans and blood tests may be used to confirm the tumors.

What causes peritoneal mesothelioma?
Peritoneal mesothelioma is caused by ingesting asbestos fibers.

How To Diagnose Peritoneal Mesothelioma? - What Is Peritoneal Mesothelioma?
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