Gestational trophoblastic disease (GTD)- Hydatiform mole. Case report of a 35 y. pat. with bleeding.

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07/14/23

Gestational trophoblastic disease (GTD)- Hydatiform mole
Case report of a 35 years old patient with bleeding and the diagnosis of a persistent gestational abnormal trophoblastic proliferation after a hydatidiform partial- Mole with invasion in the myometrium and cervical wall. Treatment laparoscopic total Hysterectomy convers to mini-laparotomy.

Gestational trophoblastic disease (GTD) is a heterogeneous group of pregnancy-related disorders characterized by abnormal proliferation of trophoblastic tissue. GTD is divided into hydatidiform moles (contain villi) and other trophoblastic neoplasms (lack villi). It encompasses the premalignant partial and complete hydatidiform mole. The non-molar or malignant forms of GTD are called gestational trophoblastic neoplasia (GTN). They include the invasive mole, choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor. These malignancies can occur weeks or years following any pregnancy but occur most commonly after a molar pregnancy.
Hydatiform mole (also known as molar pregnancy) is a subcategory of diseases under gestational trophoblastic disease (GTD), which originates from the placenta and can metastasize. It is unique because the tumor originates from gestational tissue rather than from maternal tissue. Hydatiform mole (HM) is categorized as a complete and partial mole and is usually considered the noninvasive form of gestational trophoblastic disease. Although hydatiform moles are usually considered benign, they are premalignant and do have the potential to become malignant and invasive.
Ultrasound, serum human chorionic gonadotrophin, and sometimes additional imaging such as CT, MRI, or PET can confirm the diagnosis and stage of disease.